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Homo-PROTAC pVHL30 degrader 1
CAS No. 2244684-49-7
Homo-PROTAC pVHL30 degrader 1( —— )
Catalog No. M24022 CAS No. 2244684-49-7
Homo-PROTAC pVHL30 degrader 1 is a potent pVHL30 degrader based on PROTAC.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 115 | In Stock |
|
| 10MG | 147 | In Stock |
|
| 25MG | 295 | In Stock |
|
| 50MG | 475 | In Stock |
|
| 100MG | 692 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameHomo-PROTAC pVHL30 degrader 1
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NoteResearch use only, not for human use.
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Brief DescriptionHomo-PROTAC pVHL30 degrader 1 is a potent pVHL30 degrader based on PROTAC.
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DescriptionHomo-PROTAC pVHL30 degrader 1 is a potent pVHL30 degrader based on PROTAC.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayPROTACs
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TargetE3 Ligase Ligand
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RecptorVHL
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Research Area——
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Indication——
Chemical Information
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CAS Number2244684-49-7
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Formula Weight1179.45
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Molecular FormulaC58H82N8O14S2
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Purity>98% (HPLC)
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SolubilityDMSO:150 mg/mL (127.18 mM)
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SMILESO=C(N[C@@H](C(C)(C)C)C(N1[C@H](C(NCC2=CC=C(C3=C(C)N=CS3)C=C2)=O)C[C@@H](O)C1)=O)COCCOCCOCCOCCOCCOCC(N[C@@H](C(C)(C)C)C(N4[C@H](C(NCC5=CC=C(C6=C(C)N=CS6)C=C5)=O)C[C@@H](O)C4)=O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Maniaci C, et al. Homo-PROTACs: bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation. Nat Commun. 2017 Oct 10;8(1):830.
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